Heart Problems
Mellaril can cause life-threatening heartbeat arrhythmia by prolonging the QT interval, the time between the beginning of the Q wave and the end of the T wave in the heart's electrical cycle.
Drug Interactions
Many drugs can increase the risk of Mellaril side effects, including heart problems. Patients may not be able to take Mellaril if they are using certain antibiotics, antidepressants, other drugs to treat schizophrenia or bipolar disorder, heart medications or methadone.
Other Serious Effects
Mellaril is associated with other serious side effects. These include a sometimes-permanent movement disorder (tardive dyskinesia), a life-threatening condition called neuroleptic malignant syndrome, vision problems, seizures and allergic reactions.
Common Side Effects
More common Mellaril side effects include confusion, constipation or diarrhea, drowsiness, dry mouth, headaches, hyperactivity, lack of appetite, lethargy, nausea, sexual dysfunction and weight gain.
Considerations
Because of its potential to cause very severe side effects, Mellaril is not prescribed unless other medications have failed.
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