Wednesday, July 25, 2012

Seroquel

Seroquel is an anti-psychotic medication approved by the Food and Drug Administration (FDA) to treat bipolar disorder. Bipolar disorder is a mental illness characterized by alternating periods of depression and excessively elated mood, according to the National Institute of Mental Health. Chemically, Seroquel is known as quetiapine fumarate and is legally available only by prescription.


History








Seroquel is known as an atypical antipsychotic and has been used since 1997 to help manage and stabilize the mood swings associated with bipolar disorder, according to the manufacturer's website. In 2004, it was officially approved by the FDA to treat bipolar illness. As of 2009, Seroquel was not approved for use in people under the age of 18.


How It Works


The exact method in which Seroquel works is not known, according to the manufacturer's website. However, the medical community believes that bipolar disease and other mental illnesses are caused at least in part by a chemical imbalance in the brain. Studies and patient experience have shown that Seroquel helps regulate these chemicals in the brain and reduce depression and manic behavior.


Serious Side Effects


There is a risk of serious side effects with Seroquel. Uncontrollable movements of the face and body can occur with the use of anti-psychotics such as Seroquel, and can lead to a permanent condition known as tardive dyskinesia (TD). Very high fever, muscle rigidity, confusion or shaking can result from using the drug and lead to a possibly fatal condition known as neuroleptic malignant syndrome (NMS), according to the manufacturer's website.


Common Side Effects


There are several more common side effects reported with the use of Seroquel. Drowsiness, dizziness and dry mouth may result from using Seroquel pills. Increasing intake of fluids such as water and avoiding alcoholic beverages are usually effective ways of reducing or eliminating such side effects.








Cost


As of 2009, Seroquel was available in 25-mg, 50-mg, 100-mg, 200-mg, 300-mg and 400-mg tablets. Dosage depends on the patient and prescribing doctor. Financial assistance programs are available for uninsured patients who meet certain income guidelines. Insurance co-pays depend on the individual health plan. The cost of the drug for uninsured patients paying with cash could range from about $155 for 60 25-mg tablets to about $405 for 30 400-mg pills.

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